Protocol for Comprehensive Synthetic Lethality Screens
نویسندگان
چکیده
منابع مشابه
Comprehensive analysis and prediction of synthetic lethality using subcellular locations.
The lethality of a gene is a fundamental and representative measure for understanding the function of a gene and its associated bio-systems. Recently, many research groups have started focusing on the concept of synthetic lethality. The synthetic lethality between genes is defined by the combination of mutations in two genes causing cell death. Here, we confirm that synthetic lethality and cell...
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ژورنال
عنوان ژورنال: STAR Protocols
سال: 2020
ISSN: 2666-1667
DOI: 10.1016/j.xpro.2020.100016